Addiction
60 articles on Addiction, researched and written by the Shotlee Editorial Team from primary sources.
Fat Jabs Slash Alcohol-Related Hospitalisations by More Than a Quarter
Recent analysis indicates that GLP-1 weight loss medications significantly reduce the risk of alcohol-related hospital admissions by approximately 26 percent compared to other diabetes treatments.
8 min read
Oral GLP-1 Drugs May Quiet the Brain's Food Craving Circuit
New research suggests that oral GLP-1 medications, including those used for weight loss and diabetes, might work by influencing the brain's reward pathways, potentially reducing cravings for enjoyable foods and offering insights into treating substance use disorders.
8 min read
The New Drug Melting Body Fat From 38% To 22% — And The Side Effects Patients Are Ignoring
A detailed look at the case of Gary Anderton, who achieved significant weight loss using unregulated peptides, and the critical safety risks associated with this trend.
8 min read
GLP-1 Weight-Loss Drugs Linked to Lower Risks of Addiction and Overdose
Explore the groundbreaking research linking GLP-1 medications, including Ozempic, Wegovy, Mounjaro, and Zepbound, to a reduced risk of substance use disorders and fewer addiction-related emergencies.
8 min read
Beyond Weight Loss: How GLP-1s Like Ozempic May Reshape Your Inner World
GLP-1 medications have revolutionized weight loss, but are they also changing how we feel, think, and connect? This article delves into the emerging 'Ozempic Personality' and the science behind potential mood and behavioral shifts.
9 min read
Ozempic Culture: Why Medical Weight Loss Needs Better Guardrails
As semaglutide medications become ubiquitous, we must balance their life-saving cardiovascular benefits with the dangers of normalizing extreme thinness and disordered eating behaviors.
7 min read
Beyond Hunger: GLP-1s Reveal New Insights into Compulsive Behaviors
Originally developed for diabetes, GLP-1 medications are now revealing profound insights into the neurobiology of desire, reward, and compulsion, impacting everything from food cravings to addictive tendencies.
8 min read
Beyond Weight Loss: How GLP-1s Like Ozempic May Impact Impulse and Behavior
While known for diabetes and weight management, GLP-1 receptor agonists like Ozempic and Wegovy might have a surprising effect on impulse control and behavior, according to emerging research.
6 min read
Beyond Weight Loss: The Expanding Horizon of GLP-1 Therapies
GLP-1 agonists, famously known for Ozempic and Wegovy, are making waves beyond their initial indications. While weight loss and diabetes management remain key, researchers are uncovering a broader therapeutic potential for these powerful peptide therapies.
8 min read
Beyond Appetite: How GLP-1 Drugs May Be Rewiring the Human Brain
GLP-1 receptor agonists, initially celebrated for revolutionizing diabetes and weight management, are now at the center of an unplanned, massive neuroscience experiment. Emerging data suggests these powerful medications are doing more than just regulating metabolism; they appear to be structurally and functionally altering key brain systems.
7 min read
GLP-1 Drugs: A New Frontier in Addiction Treatment?
Could the same medications revolutionizing weight loss and diabetes management also hold the key to treating addiction? Emerging research suggests GLP-1 receptor agonists may play a significant role.
8 min read
GLP-1 Drugs for Alcohol Use Disorder: The Future of Addiction Treatment?
GLP-1 receptor agonists, widely known for their efficacy in weight management and type 2 diabetes, are showing remarkable promise in addressing Alcohol Use Disorder (AUD). Emerging research suggests these injectable therapies may fundamentally alter the brain's reward pathways, offering a novel pharmaceutical path for those struggling with heavy drinking.
6 min read
Beyond Sugar: How One Doctor Lost 94 lbs & Silenced Food Noise
Dr. Stacy Smalley shares her transformative journey of losing 94 pounds by eliminating sugar, detailing how it silenced persistent cravings and improved her overall well-being. This article explores the science behind sugar's impact on appetite and provides actionable strategies for readers to achieve similar results.
8 min read
Eli Lilly 150 Years: AI, GLP-1 Advances & Future of Weight Loss
Eli Lilly celebrates 150 years with a focus on AI-driven manufacturing, new GLP-1 oral therapies, and expanded neuroscience research, signaling a major shift in pharmaceutical innovation.
8 min read
Beyond 'Ozempic Face': Navigating Skin Changes After Weight Loss
Rapid weight loss, often aided by GLP-1 medications like Ozempic and Mounjaro, can lead to significant physical transformations. While celebrated, these changes can sometimes include unwelcome skin laxity, commonly referred to as 'Ozempic Face.' This article delves into the causes, expert opinions, and potential solutions for this growing concern.
9 min read
Unexpected Discoveries: How Failed Drugs Became Medical Breakthroughs
Discover how serendipity and keen observation transformed drug development, leading to life-changing treatments for conditions ranging from diabetes and obesity to erectile dysfunction and wrinkles.
6 min read
GLP-1 Drugs: Beyond Weight Loss – New Benefits and Risks Emerge
GLP-1 medications are revolutionizing weight management and diabetes care, but their impact extends far beyond the scale. This article delves into the emerging benefits and potential risks associated with these powerful drugs, offering a comprehensive overview for patients and healthcare providers.
8 min read
What Happens to Your Body When You Take a GLP-1 Medication?
GLP-1 medications like Ozempic and Wegovy have transformed weight loss. But what exactly happens inside your body? We break down the science, mechanisms, and sustainability of peptide therapy.
8 min read
Your Gut's Natural Weight Loss System: The Science Behind GLP-1 Hormones
Discover the fascinating connection between your gut microbiome, the food you eat, and the natural hormones that regulate appetite and metabolism. Learn how these internal systems are similar to groundbreaking weight loss medications like Ozempic, Wegovy, and Mounjaro.
7 min read
Jelly Roll's 275-lb Loss: Beyond GLP-1s & Ozempic
Country star Jelly Roll has shed an astonishing 275 pounds since 2022, transforming his life without relying on GLP-1 medications like Ozempic, Wegovy, or Mounjaro. His story highlights the power of addressing food addiction through therapy, consistent exercise, and mindful eating—proving that peptide therapy alternatives can yield profound, lasting change.
4 min read
RFK Jr. and the Perils of Unapproved Peptides
The mantra 'once an accident, twice a coincidence, three times a trend' fuels bad journalism—and worse, risky medicine. A New Yorker investigation exposes clinics pushing unproven peptides for healing and longevity, backed by RFK Jr. While semaglutide proves the exception, most lack evidence and pose real harms.
5 min read
Ozempic and GLP-1 Drugs: Heart Benefits and Personal Realities
Thirty million Americans—one in eight—are turning to GLP-1 drugs like Ozempic for weight management and more, with data showing a 20% reduced risk of heart attacks and strokes. But what happens when the weight doesn't budge, as in 10% of users? This personal story explores the hype, realities, and broader implications of these medications.
4 min read
Men Coined 'Looksmaxxing,' Women Invented It: Trends & Risks
Looksmaxxing started in incel circles but mirrors women's long history of extreme beauty pursuits, from plastic surgery to Ozempic weight loss. Radical tactics like bone-smashing and crystal meth highlight its dangers, while celebrity denials fuel uncanny reactions. Unpack the cultural shift pushing men into fraught body modification.
7 min read
Kathryn Thomas: Daughter Ellie 'Getting Her Head Around' Famous Mum
Irish broadcaster Kathryn Thomas reveals her eldest daughter Ellie is starting to grasp that her mum is a public figure, amid chats about fame and family. In her new documentary Young Forever: The Death of Ageing?, she explores aesthetics, Botox normalization, peptides, and biohacking for longevity. As a 47-year-old mum, she emphasizes aging as a privilege while focusing on health for her kids' milestones.
6 min read
Untold Dangers of GLP-1s: Ozempic, Wegovy & Mounjaro Risks
Wegovy, Ozempic, and Mounjaro promise effortless weight loss with minimal risk, but new research uncovers deeper dangers like altered brain chemistry and loss of desire. On The Spectacle Podcast, Scott McKay and Melissa Mackenzie dive into the science, Melissa's personal story, and why lifestyle changes offer a safer path.
5 min read
Grim Effects of Stopping GLP-1s Like Ozempic, Study Finds
New research paints a stark picture: stopping GLP-1 drugs like Ozempic can rapidly reverse cardiovascular benefits, with risks spiking 8% after just six months. Published in BMJ Medicine, the study tracked over 333,000 adults and warns of 'metabolic whiplash.' Patients face weight regain, inflammation resurgence, and lasting scars from interruptions.
4 min read
Jelly Roll Loses 275 Pounds: No Ozempic, Just Discipline
Country star Jelly Roll has dropped 275 pounds, going from 540 to 265 lbs without Ozempic or surgery—pure discipline, faith, and addressing root causes like emotional eating and high insulin. His Men's Health cover story details the real transformation. Now, skin removal surgery awaits as the next step.
5 min read
Ozempic Cuts Depression, Anxiety, and Addiction Risk: Study
A groundbreaking study reveals that Ozempic and other GLP-1 medications like semaglutide significantly lower risks of depression, anxiety, addiction, and even suicidal behavior. Analyzing nearly 100,000 people, researchers found up to 47% reductions in related hospital visits and work absences. This could transform treatment for those with overlapping metabolic and mental health issues.
5 min read
Ozempic and Wegovy Linked to Reduced Anxiety and Depression Risk
Semaglutide, the active ingredient in Ozempic and Wegovy, is associated with a 44% decreased risk of worsening depression and 38% lower anxiety risk, per a large Swedish study. Researchers suggest potential neurobiological effects beyond weight loss. Discover how these GLP-1 agonists may support mental health in diabetes and obesity patients.
5 min read
Ozempic Turned Happy Drunk to Sad One with Horrendous Hangovers
Trey Luker-Stewart lost 60 pounds on Ozempic, but it transformed his drinking from fun nights to anxious, emotional ones with brutal hangovers. As a Dallas bar owner, he's seen a 35% drop in alcohol sales linked to GLP-1 drugs. Doctors reveal why these medications blunt alcohol's rewards and worsen next-day effects.
5 min read
Ozempic-Like Shots Curb 'Drug Noise' for Addicts: Insurance When?
GLP-1 drugs like Ozempic are silencing 'drug noise' in addicts, slashing overdoses and ER visits per a massive veterans study. Dr. Ziyad Al-Aly explains how these shots target brain reward systems. But FDA approval and insurance coverage remain years away—here's what patients need to know.
5 min read
GLP-1s Reduce Substance Addiction Risk in US Veterans: BMJ Study
An observational study in the British Medical Journal reveals GLP-1 medications like semaglutide significantly lower substance use disorder (SUD) risk in US veterans with type 2 diabetes. Compared to SGLT2 inhibitors, GLP-1s reduced new addiction risks by up to 25% and improved outcomes like 50% fewer substance-related deaths. These findings challenge traditional views on addiction and metabolic health.
5 min read
Sex-Specific GLP-1 Brain Atlas Reveals Drug Impact Differences
A new peer-reviewed study from Mount Sinai researchers has created the first sex-specific atlas of GLP-1 expression in the mouse brain, revealing dramatic differences between males and females. These insights into drugs like semaglutide and liraglutide could reshape treatments for obesity, diabetes, and even psychiatric disorders. Key hindbrain and olfactory bulb variations highlight why GLP-1 effects on appetite and weight loss differ by sex.
5 min read
Study: GLP-1s Reduce Addiction Risks Beyond Weight Loss
A groundbreaking study in the British Medical Journal reveals that GLP-1 drugs like Ozempic offer benefits far beyond weight loss and diabetes control—they significantly reduce risks of alcohol, tobacco, cannabis, and cocaine abuse. Among 606,434 US veterans with type 2 diabetes, these medications lowered substance abuse risks by up to 20%. Experts caution that while promising, more research is needed.
5 min read
Study: GLP-1 Drugs May Fight Addiction Across Major Substances
Patients on GLP-1 drugs like Ozempic report losing interest in cigarettes, alcohol, and more without effort. A physician-led study of over 600,000 VA patients reveals these medications cut addiction-related deaths by 50% and prevent new substance use disorders. This could transform treatment for alcohol, opioids, cocaine, cannabis, and nicotine.
5 min read
Ozempic May Lower Addiction Risk, New BMJ Study Shows
A groundbreaking BMJ study reveals GLP-1 drugs like Ozempic may reduce the risk of developing substance use disorders by 14% in diabetes patients. Among those with existing addictions, hospital admissions dropped 26%. While promising, these are associations from veteran health records—randomized trials are needed for proof.
5 min read
How GLP-1s Helped a Rhode Island Mom Get Sober After Alcoholism
A Rhode Island mother battled alcoholism for years, losing custody of her son, until GLP-1 drugs like Wegovy and Mounjaro helped curb her cravings in a pilot program. Gina Roberts shares her journey to two years sober, her own apartment, and family reunion. Addiction specialist Dr. Steven Klein discusses the promising role of these medications alongside traditional supports.
6 min read
GLP-1s Curb Cravings Beyond Food: 600K Study Suggests
Patients on GLP-1 drugs report losing cravings not just for food, but for cigarettes, alcohol, and more—without effort. A new study of over 600,000 people confirms dramatic reductions in overdoses, deaths, and new addictions. Could semaglutide and tirzepatide redefine addiction care?
5 min read
How GLP-1s Helped a Rhode Island Mom Get Sober After Alcoholism
A Rhode Island mother battled alcoholism for years, losing custody of her son—until GLP-1 drugs like Wegovy changed everything. In a pilot program at Open Doors transitional home, Gina Roberts stopped her cravings, got sober for two years, and rebuilt her life. Addiction specialists share why these weight-loss meds show promise for addiction recovery.
5 min read
Millennial Stars Admit to Ozempic & GLP-1 Use: Transformations
Midlife weight gain is hitting millennial stars hard, but many are turning to Ozempic and other GLP-1s for help. Celebrities including Amy Schumer, Golnesa 'GG' Gharachedaghi, and Serena Williams have openly admitted to using these medications, sharing their triumphs, side effects, and transformations. Discover their stories and the science behind these popular drugs.
5 min read
Novo's Woes Despite Ozempic's Explosive Growth
Novo Nordisk's Ozempic pioneered the GLP-1 revolution, tripling sales to 309 billion DKK in eight years. Yet shares have cratered 60% due to Eli Lilly's Mounjaro gains, trial disappointments, and looming generics. Discover the booming market's challenges and opportunities.
5 min read
Tirzepatide in Mounjaro Cuts Alcohol Intake Over 50%, Study Shows
The weight-loss drug Mounjaro's active ingredient, tirzepatide, is showing promise beyond metabolic health by slashing alcohol intake in animal models. A new study from the University of Gothenburg found it reduced voluntary consumption by over 50%, curbed binge drinking, and prevented relapse. This could signal a new avenue for treating alcohol use disorder through GLP-1/GIP receptor agonism.
6 min read
Study Finds Tirzepatide Cuts Alcohol Intake by More Than Half in Rodents
For the first time, researchers have demonstrated that tirzepatide—the key ingredient in Mounjaro—slashes voluntary alcohol consumption by more than half in rodents while curbing relapse-like drinking. Published in eBioMedicine, this University of Gothenburg study highlights effects on the brain's reward system, including dopamine modulation in the lateral septum. These findings build on prior semaglutide research and suggest potential for alcohol use disorder therapies.
6 min read
Beware the Peptide Übermensch: Biohacking's New Frontier
In Manhattan medspas and Bushwick fridges, peptides are fueling a quest for the perfect body—from GLP-1 pens vanquishing appetite to experimental vials promising telomere extension. But as biohackers chase the peptide Übermensch, what hidden costs lurk in this shift from treating illness to perfecting the self? Discover the cultural frenzy, market divides, and societal stakes.
4 min read
Mysterious Flat Affect Symptom in GLP-1 Users
Patients on GLP-1 medications are reporting a puzzling flat affect—not depression, but a sense of 'what's the point?' toward life goals and social plans. One doctor noticed this in three patients within a week, prompting deeper research into GLP-1s' impact on dopamine and motivation. Could this be an emerging side effect?
5 min read
How GLP-1 Weight Loss Drugs Revolutionized Obesity: Lessons Learned
GLP-1 weight loss drugs such as Wegovy and Zepbound have revolutionized obesity care, leading to up to 20% body weight reduction over 72 weeks. These therapies challenge old views of obesity as mere lifestyle failure, highlighting brain hunger centers, genetics, and hormones. From chronic disease recognition to equitable access, here's how they've reshaped treatment.
5 min read
GLP-1 Medications: Celebrities, Side Effects, Safer Alternatives
GLP-1 medications like Ozempic and Wegovy have surged in popularity for weight loss and Type II diabetes management, but celebrities are now sharing alarming side effects. Bunnie Xo revealed suicidal ideations after using one, while her husband Jelly Roll shed nearly 300 pounds naturally. This guide examines the risks and promotes healthier paths.
7 min read
Jelly Roll's 300-lb Weight Loss: Natural Strategies & Lessons
Jelly Roll transformed from 550 lbs to 265 lbs through disciplined lifestyle changes, avoiding GLP-1 drugs like Ozempic due to vocal health concerns. His story highlights high-protein eating, consistent movement, and overcoming food addiction. Discover actionable strategies backed by science for your own metabolic health journey.
5 min read
Tirzepatide vs Semaglutide: Weight Loss Duration After Stopping
GLP-1 medications like semaglutide and tirzepatide deliver impressive weight loss, but what happens when you stop? Pivotal trials reveal significant regain risks, underscoring obesity as a chronic condition. This guide breaks down the evidence and offers practical insights for sustained results.
4 min read
Lose 200lbs Without Ozempic: Natural Strategies That Work
At 400lbs, Devyn McGuire hit rock bottom, but two simple changes—walking and calorie control—sparked a 200lb transformation without Ozempic or Wegovy. His story proves natural methods can rival medications when backed by science and consistency. Learn the strategies, mechanisms, and mindset for your own success.
5 min read
GLP-1 Revolution: Ozempic, Wegovy, Mounjaro Rise
GLP-1 injections like Ozempic, Wegovy, and Mounjaro have exploded from niche diabetes therapies to cultural icons in weight management. While offering profound metabolic benefits, their rapid mainstreaming raises questions about proper use, side effects, and societal pressures. This guide unpacks the science, real-world stories, and future implications.
4 min read
GLP-1 Medications: Patient Stories, Science & Real Risks
GLP-1 medications like Zepbound have transformed lives, helping patients lose significant weight amid personal challenges. But rapid results come with risks like gallstones and muscle loss. This guide blends real stories with clinical insights for informed decisions.
4 min read
Naltrexone: Ozempic for Alcohol Cravings Explained
Naltrexone is gaining buzz as the 'Ozempic for alcohol' by blunting booze's euphoric reward, much like GLP-1 drugs curb food noise. This guide dives into its science, real-world use via the Sinclair Method, and clinical evidence for reducing intake. Learn if it's right for habitual drinkers aiming for moderation.
4 min read
Ozempic Era Over? BMJ Study on GLP-1 Weight Regain
The Ozempic hype may fade as a BMJ study shows users regain lost weight within 1.5 years after stopping GLP-1 drugs. These medications reduce appetite but require lifelong use and lifestyle changes for lasting results. Obesity stems from systemic issues like convenience culture and ultra-processed foods, not just willpower.
3 min read
What is 'Food Noise' and Why It's Gaining Attention with the Surge in GLP-1 Drugs?
Before starting Ozempic in spring 2023, Brenda Rogers hadn't recognized how 'food noise' drained her mental stamina. This term describes a constant preoccupation with food, tied to GLP-1 medications for diabetes and obesity. Experts explain its causes, how drugs alleviate it, and alternative approaches like therapy and diet adjustments.
4 min read
Swift Weight Rebound and Erosion of Health Advantages Upon Discontinuing GLP-1s
Individuals regain their initial weight and shed all cardiometabolic improvements in less than two years following the cessation of semaglutide or tirzepatide, according to a comprehensive meta-analysis. The research underscores the rapid nature of this regain, occurring at a pace much quicker than after non-medication interventions. Experts stress the importance of sustained strategies for maintaining benefits in chronic obesity treatment.
6 min read
Jelly Roll Turned Down Ozempic And Similar Drugs To Shed 275 Pounds! He Reveals The Shocking Motive And His Organic Approach! - Perez Hilton
Singer Jelly Roll achieved remarkable weight loss without relying on medications, choosing instead to address his eating habits as an addiction. He explains the surprising factors behind his decision and the profound impacts on his life. This natural path has revitalized his health and relationships.
4 min read
Dopamine Addiction, GLP-1 Medications & Pollution | A Third Opinion Podcast
This article examines differing viewpoints on contemporary health issues. It delves into pollution in Delhi, the increasing popularity of GLP-1 drugs, and the potential for dopamine addiction in today's society.
1 min read
Unseen Effects: Potential Impacts of GLP-1 Weight Loss Medications
GLP-1 medications, while effective for weight loss, can have various side effects. Understanding these potential impacts is crucial for informed decision-making and patient care. These medications affect different parts of the body, leading to diverse reactions based on individual physiology.
7 min read
GLP-1 Agonist Market Surge: A Metabolic Shift Transforming Diabetes Treatment and Global Obesity Management
The GLP-1 agonist market is undergoing significant expansion, fundamentally changing how Type 2 Diabetes and obesity are addressed globally. This drug class, initially for glycemic control, has become a key therapeutic option for weight management and cardiovascular risk reduction. The rising popularity of these drugs has sparked a pharmaceutical boom, with focus shifting to advanced agonists offering even greater metabolic advantages.
4 min read