Metabolic Health
60 articles on Metabolic Health, researched and written by the Shotlee Editorial Team from primary sources.
Eli Lilly's Retatrutide Shows Cardiovascular and Diabetic Benefits in Trials
Eli Lilly's investigational drug, retatrutide, has shown promising results in clinical trials, offering substantial weight loss and significant improvements in cardiovascular health and type 2 diabetes management.
7 min read
Truth About Mounjaro Jowls: Rosie O'Donnell's Facelift That Can't Hide Weight Loss
Rapid weight loss on GLP-1 medications often leads to skin laxity because the body loses subcutaneous fat faster than collagen and elastin can regenerate. This biological lag creates visible sagging, particularly in areas with high elasticity like the jawline and neck.
6 min read
New Yorkers Are Ordering Peptides Like Takeout – And California Trim Clinic Is Behind It
New York City is experiencing a surge in peptide therapy requests via telehealth platforms. This article explores the most popular compounds, safety protocols, and how to track results effectively.
8 min read
Semaglutide for Weight Loss in Adults Over 65: New Study Findings
A recent analysis of the STEP trials reveals that semaglutide, the active ingredient in popular medications like Ozempic and Wegovy, offers significant weight loss and health benefits for adults over 65 with obesity, with a safety profile comparable to younger populations.
8 min read
Fat Jabs Slash Alcohol-Related Hospitalisations by More Than a Quarter
Recent analysis indicates that GLP-1 weight loss medications significantly reduce the risk of alcohol-related hospital admissions by approximately 26 percent compared to other diabetes treatments.
8 min read
Doctors Warn a New GLP-1 Finding May Raise Your Risk of Smell Loss
Researchers analyzed nearly 877,000 patients and found a significant link between GLP-1 receptor agonists and sensory disturbances.
8 min read
I Lost 5 Stone on Mounjaro — But Now I’ve Had Enough
Natalie Lavergne transformed her health and lost 5 stone using Mounjaro, but now plans to switch to the Wegovy pill. Discover the medical realities of stopping weight loss medication.
8 min read
New “Trojan Horse” Drug Supercharges Weight Loss in Early Trials
A new hybrid molecule designed by Helmholtz Munich researchers acts as a Trojan horse to deliver metabolic compounds directly into cells, showing superior weight loss in mice compared to standard treatments.
8 min read
MOTS-C: A Peptide for Obesity Beyond GLP-1s?
While GLP-1 agonists have dominated weight loss discussions, a new peptide called MOTS-C is emerging with its own unique potential for tackling obesity and improving metabolic health. This article delves into what MOTS-C is, how it works, and its current research status.
7 min read
Why I Lost Virtually No Weight on Wegovy and Mounjaro
Explore the real-world experience of a patient who spent thousands on GLP-1 injections without significant results, and learn what worked instead.
7 min read
Bitter Hops Extract Supplement for Weight Loss
A recent study suggests a bitter hops extract supplement, Amarasate, could aid fat loss and preserve muscle mass, offering a potential alternative or complementary approach to GLP-1 medications.
8 min read
Eli Lilly Prepares FDA Run for ‘Triple-G’ Weight Loss Drug With Phase 3 Data
Eli Lilly has announced positive Phase 3 results for retatrutide, positioning the triple-agonist drug for an FDA filing in 2027 with substantial weight loss outcomes.
7 min read
Ozempic Lowers Calorie Intake For At Least A Year, Even If Hunger Returns, Trial Finds
A new 60-week clinical trial reveals that semaglutide continues to reduce calorie consumption significantly, even when subjective hunger sensations return to baseline levels.
7 min read
The Billion-Dollar Problem Limiting Access to Ozempic, Wegovy, and Zepbound
Despite clinical evidence highlighting the significant health benefits and cost-effectiveness of GLP-1 medications such as Ozempic, Wegovy, and Zepbound, many insurance plans continue to impose restrictions on patient access. This article delves into the financial and practical barriers, as well as the profound consequences for individuals seeking these transformative treatments.
7 min read
Katie Lee Biegel Shares Update on 'Incredibly Positive' GLP-1 Experience
Food Network personality Katie Lee Biegel opens up about her journey with GLP-1 medications, detailing her 'incredibly positive' experience with weight loss and enhanced well-being.
10 min read
Peptides, GLP-1s, and MAHA: A New Era in Wellness
The world of wellness is rapidly evolving, with groundbreaking advancements in peptide therapy and GLP-1 medications offering new avenues for health management and weight loss. This article delves into the science behind these innovations, explores the potential of 'MAHA' (Maximum Healthspan Aging), and discusses how individuals can navigate this exciting new frontier.
9 min read
Rosie O'Donnell: Mounjaro Changed My Life After Losing 30kg
Talk show host Rosie O'Donnell discusses her 30kg weight loss using Mounjaro, the subsequent skin concerns, and the mental health benefits of GLP-1 therapy.
6 min read
Fat Loss with GLP-1s, Muscle Loss Concerns: What Users Need to Know
GLP-1 medications are powerful tools for weight loss, but concerns are emerging about potential muscle mass loss. This article delves into what users need to know about preserving lean body mass and maintaining cardiorespiratory fitness alongside fat reduction.
7 min read
Eli Lilly to Seek FDA Approval for Obesity Drug Retatrutide
Eli Lilly announces plans to file for FDA approval of its triple-agonist obesity drug retatrutide in early 2027 following successful Phase 3 trial data.
8 min read
The New Drug Melting Body Fat From 38% To 22% — And The Side Effects Patients Are Ignoring
A detailed look at the case of Gary Anderton, who achieved significant weight loss using unregulated peptides, and the critical safety risks associated with this trend.
8 min read
The Workforce Runs on Weight Loss Drugs? Employees on GLP-1s Take Fewer Sick Days
Employees on GLP-1 medications are taking significantly fewer sick days, leading to cost savings and improved productivity. A new study reveals the economic and health impacts of drugs like Ozempic and Wegovy on the workforce.
9 min read
FDA to Review 7 Popular Peptides Touted for Weight Loss, Healing and Longevity
The FDA Pharmacy Compounding Advisory Committee is set to evaluate seven peptide substances currently available through the gray market. Experts weigh in on safety, efficacy, and future patient access.
7 min read
The Workforce Runs on Weight Loss Drugs? Employees on GLP-1s Take Fewer Sick Days
A new study reveals significant reductions in long-term sick leave for workers taking GLP-1 medications, offering insights into workplace productivity and long-term health savings.
10 min read
Rosie O'Donnell: Mounjaro Changed My Life After Losing 30kg
Talk show host Rosie O'Donnell shares her candid experience with Mounjaro, detailing her 30kg weight loss, Type 2 diabetes management, and the physical consequences of rapid fat loss.
12 min read
GLP-1s for Teen Weight Loss: A New Treatment Trend?
GLP-1 medications are rapidly changing obesity care for teens and young adults, with a notable shift away from bariatric surgery. This article delves into the latest research, potential benefits, and important considerations for this emerging trend.
7 min read
Medicare's New GLP-1 Weight-Loss Drug Program: What to Know
Medicare is launching a new pilot program to increase access to GLP-1 medications for weight loss, offering a $50 monthly copay for eligible beneficiaries. This marks a significant step in covering obesity as a medical condition.
9 min read
Semaglutide Greenlit for MASH Liver Disease Treatment
The MHRA has granted conditional approval for semaglutide to treat metabolic-associated steatohepatitis (MASH) in adults with moderate-to-advanced liver fibrosis.
7 min read
Which GLP-1 Works Best? New Meta-Study Puts Medications Head-to-Head
A comprehensive meta-analysis from the University of Georgia compares three major GLP-1 medications. Discover which drug offers the highest weight loss efficacy and what the data means for patients.
8 min read
What is the viral 'natural Ozempic' drink?
A viral trend promoting a 'natural Ozempic' drink made with gelatin and water is circulating on social media. This article delves into what the drink is, its purported benefits, and the expert opinions on its role in weight management.
6 min read
The Overlooked Nutrition Risks of Ozempic and Wegovy
New research from UCL and Cambridge highlights critical nutrition gaps in GLP-1 therapy. Discover the risks of muscle loss and deficiencies, and how to manage them safely.
8 min read
It's Called 'Nature's Ozempic', But Should You Take Psyllium Husk?
Psyllium husk is gaining viral attention for its digestive and metabolic benefits. But is it truly a weight loss solution comparable to GLP-1 medications? We break down the evidence.
8 min read
Amy Schumer Reveals Ongoing Weight Loss in New Selfie, Says C-Section Scar Makes Her a 'Warrior'
Comedian Amy Schumer recently shared a selfie highlighting her weight loss and C-section scar, opening up about her diagnosis of Cushing's syndrome and her path to health.
7 min read
People Taking GLP-1 Weight Loss Drugs Like Ozempic and Wegovy Started Moving Less
New data presented at ENDO 2026 reveals a paradox: patients on GLP-1 medications like Ozempic and Wegovy reduced their physical activity despite losing weight.
8 min read
Popular Weight-Loss Drugs Ozempic and Wegovy May Slow Biological Aging
A new clinical trial suggests that semaglutide, the active ingredient in Ozempic and Wegovy, may help slow biological processes associated with aging in adults with HIV.
8 min read
New Weight Loss Pill Beats Oral Ozempic in Major Clinical Trial
A recent Phase 3 clinical trial indicates that orforglipron offers superior blood sugar control and weight loss compared to oral semaglutide, though side effects remain a consideration.
9 min read
Semaglutide (Ozempic, Wegovy) Offers Heart Protection Beyond Weight Loss
A groundbreaking study published in The Lancet demonstrates that semaglutide, the active ingredient in Ozempic and Wegovy, provides substantial cardiovascular protection independent of the amount of weight lost. This finding reshapes our understanding of how these GLP-1 receptor agonists benefit heart health.
7 min read
The Next Ozempic: A 4-in-1 Breakthrough for Lasting Weight Loss
While Ozempic and similar GLP-1 agonists have revolutionized weight management, new research from Tufts University is exploring a novel 4-in-1 peptide that targets four hormone receptors for potentially greater efficacy and fewer side effects, moving closer to the gold standard of bariatric surgery.
6 min read
Semaglutide Linked to Fewer Bone Fractures Despite Greater Weight Loss
Discover how semaglutide, a popular GLP-1 medication, shows a surprising benefit in a recent study, potentially reducing bone fracture risk even as it aids in substantial weight loss for individuals with type 2 diabetes.
7 min read
Novo Nordisk's Semaglutide Implant Could Replace Ozempic Injections
Novo Nordisk and Vivani Medical are developing a semaglutide implant that could eliminate the need for weekly injections. Here is everything to know about the technology.
6 min read
Eli Lilly's Foundayo: A New Daily Pill Outperforming Oral Semaglutide
A groundbreaking Phase 3 trial reveals that Eli Lilly's new daily oral medication, orforglipron (Foundayo), demonstrates superior efficacy in lowering blood sugar and promoting weight loss compared to existing oral semaglutide treatments for individuals with Type 2 diabetes. This development marks a significant step forward in non-injectable peptide therapies for metabolic health.
6 min read
Beyond the Hype: Psyllium Husk for Gut Health and More
Often hailed as 'nature's Ozempic,' psyllium husk is a fiber-rich supplement gaining traction for its wide-ranging health benefits. But does it live up to the buzz? This article dives into the evidence for its impact on gut health, cholesterol, blood sugar, and weight management.
8 min read
Beyond Ozempic: A Dark Twist on Weight Loss Obsession
The rise of GLP-1 agonists has sparked a global conversation about weight loss. This article delves into the cultural phenomenon, its psychological underpinnings, and how a new horror film, 'Saccharine,' offers a chilling commentary.
7 min read
Ozempic Generics Recall: Why Cheap Semaglutide Copies Are Being Pulled
India's booming generic semaglutide market faces a credibility crisis as major manufacturers recall batches over quality concerns. Discover the implications for patient safety and treatment continuity.
9 min read
Semaglutide's Essential Status in China: A Leap for Diabetes Care
China's decision to include semaglutide on its National Essential Drug List marks a significant step in improving diabetes management across the nation, promising greater accessibility for millions.
6 min read
Ozempic, Mounjaro & More: Yale Study Exposes Risky Online GLP-1 Prescribing
New research from Yale University highlights critical gaps in the online prescribing of GLP-1 medications, raising serious concerns about patient safety and regulatory oversight.
8 min read
Beyond the Hype: Understanding Peptides for Weight Loss and Health
Curious about peptides and their role in weight loss, cholesterol management, and overall health? This article breaks down what peptides are, how they work, and what the science says about popular options like GLP-1 agonists.
7 min read
Beyond the Hype: Understanding GLP-1s and Weight Management
The rise of GLP-1 medications has revolutionized weight management. This comprehensive guide delves into semaglutide, tirzepatide, and other peptide therapies, offering insights into their efficacy, potential side effects, and how to track your progress effectively.
7 min read
Ozempic, Wegovy & Mounjaro: What Your Bones & Joints Need to Know
Millions are experiencing significant weight loss with GLP-1 medications. But what happens to your bones, joints, and muscles as the pounds drop? An orthopedic surgeon shares crucial insights.
7 min read
Beyond GLP-1: How a Simple 30g Eating Rule Led to 12lbs Lost in 6 Weeks
After years of struggling with weight, trying various diets and even GLP-1 medications with limited success, one woman discovered a simple, evidence-based eating plan that helped her shed 12 pounds in six weeks and reclaim her energy.
8 min read
Ozempic, Wegovy, Mounjaro: The GLP-1 Revolution in Weight Loss
A closer look at the groundbreaking GLP-1 medications, including Ozempic, Wegovy, and Mounjaro, and their transformative effects on weight management and overall health.
6 min read
Ozempic, Wegovy, Mounjaro: How Long Do GLP-1s Stay in Your System?
Curious about how long Ozempic, Wegovy, Mounjaro, or other GLP-1 medications stay in your system after your last dose? This comprehensive guide explores the science behind their elimination and what factors influence their duration.
7 min read
Peptides and Health: The Truth Behind the Beauty and Weight Loss Claims
Peptides are the newest buzzword in health and beauty, promising everything from wrinkle reduction to profound weight loss. But does the science actually back up the claims, and are they safe?
7 min read
Beyond the Scale: Navigating GLP-1s for Older Adults
As GLP-1 medications become more accessible, older adults are asking: 'Am I too old?' This guide explores the nuances of using these powerful drugs for weight loss in seniors, emphasizing health over age.
7 min read
Wegovy and Ozempic: The Critical Question to Prevent Weight Regain
Discover the single most important question to ask before starting GLP-1 medications like Ozempic or Wegovy. Learn how to ensure sustainable weight loss and avoid the common pitfalls of viewing these drugs as a magic cure.
8 min read
Ozempic, Wegovy, Mounjaro: Navigating the New GLP-1 Landscape
The landscape of GLP-1 medications for weight loss and chronic disease management is rapidly evolving. From new access programs to shifting pricing dynamics, understanding these advancements is crucial for patients and healthcare providers alike.
6 min read
Ozempic Culture: Why Medical Weight Loss Needs Better Guardrails
As semaglutide medications become ubiquitous, we must balance their life-saving cardiovascular benefits with the dangers of normalizing extreme thinness and disordered eating behaviors.
7 min read
Ozempic, Wegovy & Mounjaro: Navigating the GLP-1 Weight Loss Revolution
The global surge in GLP-1 medications for weight loss has sparked a vital conversation in India. While innovators like Nithin Kamath highlight affordability and potential, industry leaders like Kiran Mazumdar-Shaw urge careful consideration. This article delves into the nuances of these transformative drugs, their benefits, the hurdles to long-term adoption, and what they mean for your health journey.
7 min read
Ozempic, Wegovy & Mounjaro: Weighing Risks for Young Patients on GLP-1s
As GLP-1 medications gain traction for weight management, doctors are increasingly prescribing them to adolescents. While short-term benefits are evident, significant questions remain about the long-term implications for young, developing bodies and minds.
7 min read
Ozempic, Wegovy, Mounjaro: Your Health Journey & What to Track
The rise of GLP-1 medications like Ozempic, Wegovy, and Mounjaro has revolutionized weight management and metabolic health for millions. But beyond the prescription, embarking on this journey requires mindful tracking of your progress, symptoms, and overall well-being. This guide explores what you should be paying attention to, offering practical insights for both patients and the natural health industry.
7 min read
Unlock Your Body's Fat-Burning Hormone: The Fiber Secret
You've likely heard of GLP-1 medications like Ozempic and Wegovy. But did you know your body naturally produces this powerful hormone every time you eat? The key to maximizing your body's own GLP-1 lies in a specific type of dietary fiber. This article dives into the science behind it and reveals the top foods that can help you tap into your body's natural appetite-regulating system.
7 min read