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Tirzepatide in Mounjaro Cuts Alcohol Intake Over 50%, Study Shows
Peptide Therapy

Tirzepatide in Mounjaro Cuts Alcohol Intake Over 50%, Study Shows

The weight-loss drug Mounjaro's active ingredient, tirzepatide, is showing promise beyond metabolic health by slashing alcohol intake in animal models. A new study from the University of Gothenburg found it reduced voluntary consumption by over 50%, curbed binge drinking, and prevented relapse. This could signal a new avenue for treating alcohol use disorder through GLP-1/GIP receptor agonism.

Shotlee··6 min read
Study Finds Tirzepatide Cuts Alcohol Intake by More Than Half in Rodents
GLP-1 Medications

Study Finds Tirzepatide Cuts Alcohol Intake by More Than Half in Rodents

For the first time, researchers have demonstrated that tirzepatide—the key ingredient in Mounjaro—slashes voluntary alcohol consumption by more than half in rodents while curbing relapse-like drinking. Published in eBioMedicine, this University of Gothenburg study highlights effects on the brain's reward system, including dopamine modulation in the lateral septum. These findings build on prior semaglutide research and suggest potential for alcohol use disorder therapies.

Shotlee··6 min read
Study: Ozempic, Wegovy NAION Risk Twofold Higher vs. SGLT2i Drugs
GLP-1 Medications

Study: Ozempic, Wegovy NAION Risk Twofold Higher vs. SGLT2i Drugs

New research from Veterans' Affairs shows Ozempic and Wegovy users face double the risk of NAION—a serious vision loss condition—compared to SGLT2i drugs. Published in JAMA Ophthalmology, the study urges doctors to warn patients about potential permanent blindness from semaglutide-based GLP-1 medications. As lawsuits mount, understand the implications for diabetes and weight management.

Shotlee··5 min read