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📖Complete Guide✅Updated 2026🔬Evidence-Based

Thymosin Alpha 1 Guide (2026)

Complete Guide & Evidence (2026)

FDA-orphan-drug designated immune modulator. Enhances T-cell function, NK cell activity, and dendritic cell maturation.

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Dashboard
Your complete health overview in one place
🔥
14-day streak
Logged 18 of 18 scheduled shots
Next Shot Reminder
⌄
ACTIVE MEDICATIONS
Thymosin Alpha 1B12
THYMOSIN ALPHA 1
🔥 14
2
days away
Thursday · 7.5mg
⌄
Medication Supply
Thymosin Alpha 1
6.2 / 10 mg · Vial
~42 days left · Mar 15
B12
4.4 / 5 ml · Vial
~88 days left · May 8
Retatrutide
1.2 / 5 mg · Vial
~6 days left · refill soon
Medication Levels
7 Days2 Weeks1 Month90 Days
CURRENT LEVEL
5.42mg
Mar 6
Today
ACTIVE MEDICATIONS
Thymosin Alpha 1Retatrutide
0mg2.7mg5.4mg
18
Total Injections
💉 All time
122/78
Average BP
🩺 mmHg
8.4
Avg Mood
😊 /10
Health Chart
1mAll
218.6lb
↓ 8.4 lb · 3.7%
WeightInjectionsBPMood
2282222162102277.5mg7.5mg4mg10mg218
Feb 6Feb 14Feb 22Mar 2Today
Photos
12 photos · 2w streak
Week 1
Week 7
Today
Scheduled Reminders
Weight
Due today
Mood
Done
Blood Pressure
Tomorrow
Body Measurements
In 3 days
Dashboard
Your complete health overview in one place
🔥
14-day streak
Logged 18 of 18 scheduled shots
Next Shot Reminder
⌄
ACTIVE MEDICATIONS
Thymosin Alpha 1B12
THYMOSIN ALPHA 1
🔥 14
2
days away
Thursday · 7.5mg
⌄
Medication Supply
Thymosin Alpha 1
6.2 / 10 mg · Vial
~42 days left · Mar 15
B12
4.4 / 5 ml · Vial
~88 days left · May 8
Retatrutide
1.2 / 5 mg · Vial
~6 days left · refill soon
Medication Levels
7 Days2 Weeks1 Month90 Days
CURRENT LEVEL
5.42mg
Mar 6
Today
ACTIVE MEDICATIONS
Thymosin Alpha 1Retatrutide
0mg2.7mg5.4mg
18
Total Injections
💉 All time
122/78
Average BP
🩺 mmHg
8.4
Avg Mood
😊 /10
Health Chart
1mAll
218.6lb
↓ 8.4 lb · 3.7%
WeightInjectionsBPMood
2282222162102277.5mg7.5mg4mg10mg218
Feb 6Feb 14Feb 22Mar 2Today
Photos
12 photos · 2w streak
Week 1
Week 7
Today
Scheduled Reminders
Weight
Due today
Mood
Done
Blood Pressure
Tomorrow
Body Measurements
In 3 days
01WHAT TO TRACK

Thymosin Alpha-1 Immune Modulation

01
🔬
Innate Immunity
Activates dendritic cells and NK cells. Upregulates TLR (Toll-like receptor) signaling. Enhances first-line pathogen response
02
🔬
Adaptive Immunity
Promotes Th1 over Th2 immune polarization. Enhances CD4+ and CD8+ T-cell activity. Improves vaccine antigen presentation
03
🔬
Cytokine Regulation
Upregulates IL-2, IFN-γ, IFN-α production. Reduces immunosuppressive IL-10 in cancer contexts. Reduces NF-κB-driven inflammation
02BACKGROUND

Clinical Record

Countries where Zadaxin (thymosin alpha-1) is approved for hepatitis B/C treatment.

Subcutaneous dose per injection — approved Zadaxin dosing unit for hepatitis.

Decades of clinical use in hepatitis B/C, cancer adjuvant, and immunodeficiency contexts.

03WHAT TO TRACK

Applications

01
📊
Clinical / Approved
Chronic Hepatitis B — first-line and adjunct to antiviral. Chronic Hepatitis C — adjunct to interferon therapy. Cancer — immune adjuvant during chemotherapy. COVID-19 — immune modulator (used in China
02
🔬
Research / Off-Label
Immune senescence in aging — restoring thymic function. Chronic Lyme and mold illness — immune modulation. Post-viral fatigue and Long COVID. Vaccine adjuvant — improving antibody response
04DEEP DIVE

Thymosin Alpha-1 Protocol

Safety note: Thymosin alpha-1 has an excellent safety record from decades of Zadaxin clinical use. Common stacks include LL-37 (antimicrobial synergy) and BPC-157 (gut-immune axis support). Track all immune markers and energy in the Shotlee app.

05WHAT TO TRACK

Vital Protocol FAQs

01
🔬
What is thymosin alpha-1?
Thymosin alpha-1 (Tα1) is a 28-amino acid peptide naturally produced by the thymus gland. It is the active ingredient in Zadaxin, an FDA-approved biological for hepatitis B in several countries. Tα1 m
02
🔬
What conditions is thymosin alpha-1 used for?
Clinically, thymosin alpha-1 (Zadaxin) is approved in 35+ countries for chronic hepatitis B, hepatitis C (adjunct to interferon), and as an immune adjuvant in cancer chemotherapy. It was used in China
03
💉
What is the thymosin alpha-1 dosing protocol?
The FDA/EMA-approved Zadaxin dose for hepatitis is 1.6 mg subcutaneous twice weekly for 6–12 months. Biohacking protocols typically use 1.6 mg subcutaneous twice weekly or 1.6 mg 3× per week during ac
04
🔬
Is thymosin alpha-1 the same as thymalin?
No. Thymosin alpha-1 (Tα1) and thymalin are different thymic peptides with overlapping but distinct effects. Thymalin is a polypeptide extract from bovine thymus, primarily studied in Russian aging re
06FAQ

Guide FAQs

FDA-orphan-drug designated immune modulator. Enhances T-cell function, NK cell activity, and dendritic cell maturation.

Yes. Shotlee supports tracking Thymosin Alpha 1 doses, side effects, and health metrics. It is free to use.

Free · Always

Track Your Thymosin Alpha 1 Protocol in Shotlee

Free dose logging, side effect tracking, and health metric monitoring for your complete protocol.

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📚References & sources

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