What is Thymosin Alpha-1?

Thymosin Alpha-1 (Tα1) is a naturally occurring 28-amino acid peptide first isolated from the thymus gland. The thymus is central to immune system development — it is where T-cells mature before entering circulation. Thymosin Alpha-1 has potent immunomodulatory effects, particularly on dendritic cells, natural killer cells, and CD4+ and CD8+ T-lymphocytes.

It is marketed as Zadaxin (thymalfasin) and is approved in over 35 countries for treatment of hepatitis B and C, certain cancers, and as an adjuvant to vaccines. In the longevity and biohacker community, it is used to optimize immune function and slow age-related thymic involution.

Research compound for off-label longevity use. Not FDA-approved in the US for immune optimization. Always use under medical supervision with regular immune function monitoring.

FAQ

What is Thymosin Alpha-1?

A thymus-derived peptide that modulates T-cell function and innate immunity. Approved in 35+ countries for hepatitis B/C. Used off-label by longevity enthusiasts for immune optimization.

What is the typical protocol?

1–1.6mg twice weekly by subcutaneous injection. Typical cycles run 4–12 weeks. Clinical hepatitis protocols use 1.6mg twice weekly for 6 months.

What should I track?

Injection frequency, energy and illness frequency, and immune labs (CD4/CD8, NK cells) if monitored by your physician. Shotlee lets you log all of this alongside your dose history.

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