What is Compounded Semaglutide?

Compounded semaglutide is the same active molecule as Wegovy and Ozempic, but prepared by licensed compounding pharmacies. Due to ongoing Wegovy shortages, the FDA has allowed compounding pharmacies to produce semaglutide.

Compounded versions are significantly cheaper (often $150-400/month vs $1,000+ for brand) but come with trade-offs in quality assurance and consistency.

Important: Compounded medications are NOT FDA-approved. Quality varies by pharmacy. Always use a reputable 503A or 503B compounding pharmacy.

Dose Matching Guide

Wegovy to Compounded Semaglutide
0.25mgWegovy
=
0.25mg (10 units from 2.5mg/mL vial)Compounded
Initiation dose
0.5mgWegovy
=
0.5mg (20 units from 2.5mg/mL vial)Compounded
Week 5+
1.0mgWegovy
=
1.0mg (40 units from 2.5mg/mL vial)Compounded
Week 9+
1.7mgWegovy
=
1.7mg (34 units from 5mg/mL vial)Compounded
Week 13+
2.4mgWegovy
=
2.4mg (48 units from 5mg/mL vial)Compounded
Maintenance

Choosing a Safe Compounding Pharmacy

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503A or 503B Licensed

503B pharmacies have stricter FDA oversight. 503A pharmacies compound on individual prescription basis.

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Third-Party Testing

Reputable pharmacies provide certificates of analysis (COA) showing purity and potency.

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Requires Prescription

Legitimate compounding pharmacies always require a valid prescription from a licensed provider.

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Too Good to Be True Pricing

Extremely cheap semaglutide ($50-100/month) may indicate poor quality or counterfeit product.

FAQ

Is compounded semaglutide as effective as Wegovy?

If properly formulated, yes. The molecule is identical. However, quality control varies between pharmacies, which may affect consistency.

Why is compounded semaglutide so much cheaper?

No R&D costs, no FDA approval process, and no brand marketing. Compounding pharmacies just need to source the raw material and mix it properly.

Will compounded semaglutide always be available?

No. Compounding is only allowed during drug shortages. Once Wegovy supply normalizes, the FDA may restrict compounded semaglutide production.

Track Your Compounded Semaglutide

Shotlee supports tracking compounded peptides with custom dosing. Log vials, units, and injection sites.

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