Compounded Semaglutide Guide

Compounded semaglutide is the same active molecule as Ozempic and Wegovy, but prepared by licensed compounding pharmacies rather than Novo Nordisk.

Why it exists: The FDA allows compounding during drug shortages. Since Ozempic and Wegovy have been on the shortage list, compounding pharmacies can legally produce semaglutide.

Key difference: Compounded medications are NOT FDA-approved. They don't undergo the same testing and quality control as brand-name drugs. Quality depends entirely on the pharmacy.

Compounded semaglutide typically comes in vials with a concentration (e.g., 2.5mg/mL or 5mg/mL). You'll draw up your dose using insulin syringes.

Example: From a 2.5mg/mL vial, to get 0.25mg dose, draw up 10 units (0.1mL). For 0.5mg, draw 20 units (0.2mL). For 1.0mg, draw 40 units (0.4mL).

Tip: Use Shotlee's peptide reconstitution calculator to verify your dosing calculations and track your vial usage.