A hot drink like green tea may mimic the effects of GLP-1 inhibitors for weight loss, according to recent research. A scientific review highlights natural dietary compounds that replicate GLP-1 actions, offering potential accessibility benefits.
What Are GLP-1 Inhibitors?
GLP-1 (glucagon-like peptide-1) is a gut hormone that regulates blood sugar and appetite. GLP-1 inhibitors, popular injections, help diabetic patients control blood sugar and achieve weight reduction. These medications are available via the NHS for qualifying patients.
Natural Compounds Mimicking GLP-1 Effects
In 2025, researchers from Heliopolis University in Cairo published a review in Toxicology Reports. The study examined how dietary compounds influence GLP-1, driven by the high cost and limited access to injections, plus side effects like vomiting, diarrhea, and cramps.
Researchers noted: "It's about increasing treatment options and personalizing it to each patient's preferences and needs."
Identified compounds include:
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- Green tea
- Ginger
- Cinnamon
- Wheat
- Berberine (from plants)
Expert Perspective
Bariatric surgeon Mir Ali, medical director at Memorial Care Surgical Weight Loss Centre, emphasizes these are not alternatives to GLP-1 medications. "Natural ingredients may help boost metabolism. However, it is a mild effect," he stated.
Ali explained they work differently: stimulating the central nervous system (caffeine), promoting fat burning (green tea extract, capsaicin), or activating enzymes (berberine).
Supporting Research on Green Tea
Prior studies link green tea to weight loss. A Journal of Functional Foods paper recommended catechin-enriched green tea.
Authors reported: "Average visceral fat area, body weight, and body fat were reduced significantly by catechin-enriched green tea treatment... Thus, consumption of the catechin-enriched green tea beverage for 12 weeks induced visceral fat loss in Chinese adults with a high proportion of abdominal visceral fat."
They added: "In recent years, there have been many studies on the beneficial effects of green tea in treating obesity and improving glucose and lipid metabolism."
Key Takeaways
- Natural compounds show promise but offer mild effects compared to GLP-1 inhibitors.
- Consult healthcare providers before relying on diet for weight management.
- Research supports green tea's role in visceral fat reduction.