Shotlee LogoShotlee
Blog
Download on theApp Store
Get it onGoogle Play
Skip to main content
Doctor: You May Regain Weight After Stopping GLP-1 Drugs - Featured image
GLP-1 Medications

Doctor: You May Regain Weight After Stopping GLP-1 Drugs

Shotlee Editorial Team
Written by Shotlee Editorial TeamHealth Research & Writing
·January 20, 2026·1 min read

On this page

  • Dr. Karan Rajan's Key Insights
  • Lifestyle Changes Are Essential
  • Not Forever for Everyone
  • Important Safety Notes

Track Smart

Calculate active GLP-1 levels automatically with Shotlee.

Download →

Doctor Karan Rajan explains why you might regain weight after quitting GLP-1 drugs: they mimic treatments for chronic conditions like high blood pressure. Obesity requires ongoing management with lifestyle factors like diet, exercise, and sleep. Not everyone needs GLP-1s forever, but stopping without changes risks relapse.

Share

On this page

  • Dr. Karan Rajan's Key Insights
  • Lifestyle Changes Are Essential
  • Not Forever for Everyone
  • Important Safety Notes

GLP-1 medications, such as Ozempic and Wegovy, suppress appetite and aid weight loss for eligible NHS patients. However, they are not a permanent cure for obesity.

Dr. Karan Rajan's Key Insights

In a popular TikTok video, Dr. Karan Rajan (known as Dr. Raj online) addresses a common question: "Do you have to take a GLP-1 forever?"

He describes obesity as a chronic relapsing condition, cautioning against short-term use without comprehensive weight management.

"An uncomfortable truth: GLP-1s aren't cures. They act like blood pressure pills or statins—if you stop, you lose the effect."

Lifestyle Changes Are Essential

To sustain long-term health benefits beyond medication adherence, Dr. Rajan emphasizes non-negotiable lifestyle adjustments.

Precision tracking for your journey

Join thousands using Shotlee to accurately track GLP-1 medications and side effects.

📱 Get the Shotlee App

Track your GLP-1 medications, peptides, and health metrics on the go with our mobile app!

Download on theApp Store
Get it onGoogle Play
  • Muscle mass preservation through strength training
  • Behavioral changes for sustainable habits
  • Quality sleep
  • High fiber intake
  • Adequate protein consumption
  • Stress management
  • Improved insulin sensitivity

Apps like Shotlee can help track GLP-1 doses and monitor these factors for better compliance.

Not Forever for Everyone

Dr. Rajan compares GLP-1s to eczema management: some avoid triggers without meds, others use occasional relief, and some need daily treatment.

All weight management medications must pair with a reduced-calorie diet and increased physical activity.

Important Safety Notes

  • Only use prescribed medications—never self-medicate
  • They may cause serious side effects and aren't safe for everyone
  • Consult a doctor for referral to specialist weight management services

Source Information

Originally published by EXPRESS.Read the original article →

Read next

Keep exploring

More on Ozempic

Articles covering Ozempic dosing, side effects, and clinical updates.

What's the Deal with Peptides? The Hyped Market Under FDA Review
Health & Wellness

What's the Deal with Peptides? The Hyped Market Under FDA Review

An in-depth look at the FDA's review of unregulated peptide therapy, the safety concerns raised by experts, and the conflict between industry demand and clinical evidence.

8 min read
Eli Lilly, Novo Nordisk Address Awareness Gap for Medicare’s $50 GLP-1 Program
Health & Wellness

Eli Lilly, Novo Nordisk Address Awareness Gap for Medicare’s $50 GLP-1 Program

Learn how the new Medicare GLP-1 Bridge program works, which drugs are covered, and why major pharmaceutical companies are leading the awareness push for the $50 copay initiative.

8 min read
Eli Lilly's Retatrutide Shows Cardiovascular and Diabetic Benefits in Trials
Medical Research

Eli Lilly's Retatrutide Shows Cardiovascular and Diabetic Benefits in Trials

Eli Lilly's investigational drug, retatrutide, has shown promising results in clinical trials, offering substantial weight loss and significant improvements in cardiovascular health and type 2 diabetes management.

7 min read

Same topic: GLP-1

All GLP-1 articles →
Samsung Biologics Acquires PolyPeptide for $1.8 Billion to Expand Peptide Therapeutics
Pharmaceutical Industry News

Samsung Biologics Acquires PolyPeptide for $1.8 Billion to Expand Peptide Therapeutics

Samsung Biologics has announced a major acquisition of PolyPeptide Group AG for $1.8 billion, marking a strategic expansion into the rapidly growing peptide therapeutics market, particularly for GLP-1 drugs.

8 min read

More in GLP-1 Medications

Prof Urges Caution on Funding Wegovy Rollout
GLP-1 Medications

Prof Urges Caution on Funding Wegovy Rollout

Prof Jim Mann cautions against broad funding for Wegovy, urging focus on high-risk patients like those with heart disease or diabetes. He emphasizes integrating GLP-1 medications into a national obesity strategy with mandatory nutritional support to prevent weight regain. Early data highlights side effect risks and the need for dietary counseling.

2 min read
Ozempic Book Reframes Obesity Views in GLP-1 Era
GLP-1 Medications

Ozempic Book Reframes Obesity Views in GLP-1 Era

A new book, 'Off the Scales,' reveals how Ozempic and GLP-1 drugs are reshaping societal views on obesity. Author Aimee Donnellan details their development, profound weight loss effects, and the urgent need for medical approaches to this growing crisis. Learn why these therapies mark a turning point in weight management.

2 min read
Ozempic's Rise: GLP-1 Drugs Curbing US Obesity Rates
GLP-1 Medications

Ozempic's Rise: GLP-1 Drugs Curbing US Obesity Rates

CDC 2024 data shows US obesity rates dipping for the first time in decades, thanks to Ozempic and GLP-1 drugs. Originally a diabetes treatment, these medications mimic GLP-1 hormones for dramatic weight loss. Learn the serendipitous science behind them and their broader implications.

2 min read
Share this article
  1. Home
  2. Blog
  3. Doctor: You May Regain Weight After Stopping GLP-1 Drugs
Shotlee Editorial Team — Health Research & Writing
Written by

Shotlee Editorial Team

Health Research & Writing

Shotlee’s guides and articles are researched and written in-house by the Shotlee Editorial Team. We build every page from primary sources — FDA labels, official prescribing information, and peer-reviewed clinical trials — and cite them directly. Our content is educational and is not a substitute for advice from your own healthcare provider.

View all articles by Shotlee Editorial Team
Shotlee LogoShotlee

Your comprehensive health tracking companion. Track, analyze, and optimize your journey with advanced metrics and community support.

Product

  • Medication Trackers
  • Health Guides
  • Calculators
  • Compare Medications
  • Pricing

Resources

  • Health Blog
  • Support Center

Legal

  • Privacy Policy
  • Terms of Service
  • Community Guidelines
  • Refund Policy

© 2026 Shotlee. All rights reserved.

Made with for the community♥ for the community