Semaglutide vs Bariatric Surgery Guide (2026)
Complete Guide & Evidence (2026)
Semaglutide vs bariatric surgery for obesity. Weight loss comparison (15-17% vs 25-35%), cost analysis over 5 years, durability, and complication rates.
Key Weight Loss Numbers
Mean total body weight loss in STEP trials at 68 weeks on 2.4 mg/week semaglutide.
Mean TBWL in SURMOUNT-1 at 72 weeks on 15 mg/week tirzepatide.
Average total body weight loss from Roux-en-Y gastric bypass at 1–2 years post-surgery.
Decision Framework
Guide FAQs
Semaglutide vs bariatric surgery for obesity. Weight loss comparison (15-17% vs 25-35%), cost analysis over 5 years, durability, and complication rates.
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📚References & sources
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