Orforglipron Tracker
Track the New Once-Daily Oral GLP-1 Pill
Orforglipron is Eli Lilly's once-daily oral GLP-1 receptor agonist — no needles, no fasting requirements. Track your doses, weight, and side effects with the free Shotlee app starting day one of your prescription.
What is Orforglipron?
Orforglipron is the first true oral small-molecule GLP-1 receptor agonist — meaning it's not a peptide that degrades in the stomach, but a small organic molecule designed to activate GLP-1 receptors without injection or fasting requirements.
Phase 3 trials over 72 weeks showed weight loss of 7.8% (low dose), 9.3% (medium dose), and 12.4% (high dose) — comparable to injectable semaglutide. Blood sugar control in diabetes trials was also significant.
Unlike Rybelsus (oral semaglutide), orforglipron does not need to be taken 30 minutes before food on an empty stomach. Take it anytime, like any regular daily tablet. FDA approval expected mid-2026.
Orforglipron Dose Escalation
Initial dose to assess tolerance and minimize GI side effects
Intermediate dose — most patients see meaningful weight loss at this level
Maximum dose — 12.4% average weight loss in Phase 3 trials
Tracking Features
FAQ
What is orforglipron?
A once-daily oral small-molecule GLP-1 receptor agonist from Eli Lilly. No injections, no fasting requirements. Phase 3 trials show up to 12.4% weight loss. FDA approval expected mid-2026.
How do I track orforglipron?
Open Shotlee, select orforglipron, log your daily tablet, and track weight and side effects. Daily reminders keep you consistent.
Does orforglipron require refrigeration or fasting?
No to both. It's a room-temperature tablet you can take anytime — unlike Rybelsus which requires 30 minutes fasting before food.
Is Shotlee free for orforglipron tracking?
Yes — orforglipron tracking is completely free forever. Premium AI features are available optionally.