Storage Requirements by Medication

Ozempic
Unopened:36-46°F (refrigerated)
In Use:Up to 56 days at room temp (≤86°F)
Keep cap on, protect from light
Wegovy
Unopened:36-46°F (refrigerated)
In Use:Up to 28 days at room temp (≤77°F)
Stricter temp limit than Ozempic
Mounjaro
Unopened:36-46°F (refrigerated)
In Use:Up to 21 days at room temp (≤86°F)
Single-use pens, no storage after first use
Zepbound
Unopened:36-46°F (refrigerated)
In Use:Up to 21 days at room temp (≤86°F)
Same as Mounjaro (tirzepatide)
Compounded
Unopened:36-46°F (refrigerated)
In Use:28-30 days refrigerated
Check pharmacy instructions; shorter shelf life

Storage Do's and Don'ts

✓ DO

  • • Store unopened pens in the refrigerator door
  • • Keep the cap on when not in use
  • • Let refrigerated pen warm 15-30 min before injecting
  • • Write the date you opened it on the pen
  • • Store away from light (in box or drawer)

✗ DON'T

  • • Never freeze your medication
  • • Don't store in direct sunlight or heat
  • • Don't leave in a hot car
  • • Don't use if solution is cloudy or discolored
  • • Don't use after expiration date

What If My Medication Got Warm or Cold?

Brief temperature excursion: If your pen was left out for a few hours but stayed under 86°F, it's likely fine. GLP-1 medications have some stability buffer.

Prolonged heat exposure: If left in a hot car (over 100°F) for hours, the medication may be degraded. When in doubt, contact your pharmacist.

Freezing: If your medication froze, do NOT use it. Freezing damages the peptide structure and can make it ineffective or dangerous.

Visual check: If the solution looks cloudy, has particles, or is discolored (should be clear and colorless), don't use it.

FAQ

Can I travel with my GLP-1 pen unrefrigerated?

Yes, for short trips. Ozempic is stable at room temp for up to 56 days, Wegovy for 28 days. Use a cool pack if traveling in extreme heat.

Should I inject cold medication?

Cold injections are safe but may sting more. Let the pen sit at room temperature for 15-30 minutes before injecting for comfort.

How do I store compounded semaglutide?

Compounded vials should stay refrigerated at all times. Once reconstituted, most pharmacies recommend using within 28-30 days.

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