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GLP-1 Medications

Novo's Wegovy Oral Pill Shows Strong Early US Momentum vs Lilly

Dr. Adrian Vale, MD
Reviewed by Dr. Adrian Vale, MDInternal Medicine · Board-Certified Obesity Medicine
·January 17, 2026·1 min read

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  • Stock Boost and Strategic Launch
  • Intensifying Competition with Eli Lilly
  • Prescription Projections

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Novo Nordisk's new oral Wegovy pill achieved 3,071 retail prescriptions in its first four days in the US. This strong start signals competition with Eli Lilly's offerings. Analysts predict up to $1 billion in 2024 sales if momentum continues.

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On this page

  • Stock Boost and Strategic Launch
  • Intensifying Competition with Eli Lilly
  • Prescription Projections

Novo Nordisk's newly launched Wegovy weight-loss pill demonstrates promising early performance in the United States. Initial prescription data reveals about 3,071 retail prescriptions filled in the first four days following its January 5 launch. This marks the debut of the first oral GLP-1 weight-loss drug on the market.

Stock Boost and Strategic Launch

Following the positive news, Novo Nordisk's shares surged 6.5%, hitting their highest level since September. The company prioritizes the US rollout to sidestep supply constraints, targeting cash-paying patients via major pharmacies and telehealth services.

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Intensifying Competition with Eli Lilly

The pill bolsters Novo's efforts to counter US rival Eli Lilly amid rising competition. An FDA decision on Lilly's experimental oral pill looms by April. While early data is preliminary, analysts warn of potential impacts from pricing and insurance shifts.

Prescription Projections

  • UBS projects that exceeding 400,000 first-quarter prescriptions could match Lilly's Zepbound and surpass Wegovy's injectable launch.
  • Estimates suggest the pill may generate around $1 billion in sales this year with first-mover edge.

Though injectables will dominate, experts anticipate oral GLP-1 options will broaden access for needle-averse patients, expanding the weight management market.

Source Information

Originally published by EuropeTimes.Read the original article →

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Dr. Adrian Vale, MD — Internal Medicine · Board-Certified Obesity Medicine
Medically reviewed

Dr. Adrian Vale, MD

Internal Medicine · Board-Certified Obesity Medicine

Dr. Adrian Vale is a board-certified internal medicine physician with a clinical focus on obesity medicine and metabolic health. He reviews Shotlee guides and articles on GLP-1 medications, peptide therapy, and weight-management protocols for clinical accuracy.

View all articles reviewed by Dr. Adrian Vale, MD
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