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What Causes Hair Loss on GLP-1?

Key insight: It's not the medication directly—it's the rapid weight loss. This condition is called telogen effluvium.

When your body experiences stress (rapid weight loss, caloric deficit, nutritional deficiencies), hair follicles prematurely enter the "resting" (telogen) phase. 2-3 months later, this hair falls out.

In clinical trials, about 3-5% of participants on semaglutide and tirzepatide reported hair loss, compared to 1% on placebo. The same rate is seen with bariatric surgery and crash diets.

Hair Loss Timeline

Month 1-2No ChangesHair looks normal. Follicles are beginning to shift phases.
Month 3-4Shedding StartsIncreased hair in brush/shower. Can lose 100-300 hairs/day vs normal 50-100.
Month 5-6Peak SheddingMaximum hair loss period. May notice thinning, especially at temples/crown.
Month 7-12RegrowthNew hair begins growing. Full recovery typically within 6-12 months.

Prevention Strategies

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Adequate Protein

Hair is made of keratin (protein). Aim for 1g protein per lb of target body weight. Low protein = more hair loss.

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Check Iron & Ferritin

Iron deficiency is a major cause of hair loss, especially in women. Get labs done and supplement if low.

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Biotin & Zinc

Both support hair health. Consider 5-10mg biotin and 15-30mg zinc daily. Results take 3-6 months.

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Slower Weight Loss

Losing 1-1.5 lbs/week vs 2-3 lbs/week significantly reduces telogen effluvium risk.

When to See a Doctor

Telogen effluvium is temporary and self-resolving. However, see a dermatologist if:

  • • Hair loss continues past 12 months
  • • You notice patchy bald spots (could be alopecia areata)
  • • Scalp is itchy, red, or flaky (could be fungal or inflammatory)
  • • You have other symptoms like fatigue, weight gain, cold intolerance (could be thyroid)

FAQ

Should I stop Ozempic if I'm losing hair?

Usually not necessary. The hair loss is from weight loss, not the drug. Stopping won't bring hair back faster. Talk to your doctor about slowing your dose titration.

Will my hair grow back?

Yes, in almost all cases. Telogen effluvium is temporary. Once weight stabilizes and nutrition improves, hair regrows within 6-12 months.

Does Mounjaro cause more hair loss than Ozempic?

Clinical trials show similar rates (~3-5%). Because Mounjaro often causes faster weight loss, some users may notice more pronounced shedding.

Track Side Effects with Shotlee

Log hair changes, nutrition, and weight loss rate to identify patterns and share with your doctor.

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