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Oprah discloses how GLP-1 drugs resulted in her sobriety

Dr. Adrian Vale, MD
Reviewed by Dr. Adrian Vale, MDInternal Medicine · Board-Certified Obesity Medicine
·December 31, 2025·2 min read

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Media mogul Oprah Winfrey has openly discussed her use of GLP-1 drugs for shedding pounds, but she recently shared a surprising outcome: the end of her alcohol consumption. This change has revitalized her sense of vitality and openness, while offering insights into obesity and personal growth. She encourages others to embrace available options without self-blame.

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The prominent media figure has been open about employing GLP-1 drugs for shedding excess weight, yet she recently shared an unforeseen benefit from the treatment: an end to her alcohol intake.

'I used to enjoy tequila immensely,' Winfrey stated to People in a December 30 interview. 'I actually consumed 17 shots on a single evening.'

However, since starting GLP-1s, the 71-year-old revealed that her era of surpassing everyone else's drinking at social gatherings has concluded.

'The realization that I no longer crave it at all,' she remarked, 'is truly remarkable.'

This sense of wonder extends to nearly every area of her existence.

'I sense greater liveliness and energy than ever before,' Winfrey, who acknowledged using a GLP-1 in 2023, expressed. 'I'm no longer berating myself. I barely recognize the person I've transformed into. Yet, she's a content individual.'

Furthermore, she reports increased vitality for her close relationships, including her supportive partner Stedman Graham.

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'It seems I have more capacity to offer others,' she added. 'I'm simply more receptive to everything.'

Moreover, the guilt she once carried regarding her challenges with sustaining weight reduction has vanished.

'I steered clear of the term 'obesity' because it implied a lack of control,' she clarified. 'But I've come to grasp that overeating isn't the root cause of obesity. Instead, obesity triggers overeating. This has been the most liberating insight of my adulthood.'

For individuals facing comparable hurdles, her advice is straightforward: it's not their responsibility.

'I urge everyone to cease self-criticism for factors like genetics and uncontrollable surroundings,' she urged. 'I want folks to access the knowledge, and decide accordingly—whether opting for these drugs or continuing with dietary efforts. Health tracking apps like Shotlee can assist in monitoring advancements.'

Related Celebrity Perspectives

Other stars, including Serena Williams and Amy Schumer, have also commented on Ozempic and similar weight management pharmaceuticals.

Source Information

Originally published by NBC Chicago.Read the original article →

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Dr. Adrian Vale, MD — Internal Medicine · Board-Certified Obesity Medicine
Medically reviewed

Dr. Adrian Vale, MD

Internal Medicine · Board-Certified Obesity Medicine

Dr. Adrian Vale is a board-certified internal medicine physician with a clinical focus on obesity medicine and metabolic health. He reviews Shotlee guides and articles on GLP-1 medications, peptide therapy, and weight-management protocols for clinical accuracy.

View all articles reviewed by Dr. Adrian Vale, MD
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