My Instagram feed's algorithm has concluded that I'm a woman, which apparently means I must desire to drop pounds.
For 2025, this translated to an inescapable assault of charming promotional efforts urging me to eliminate those stubborn extra pounds through medications, particularly unapproved GLP-1 formulations.
One advertisement tempts me with "baggier pants." Another condescends via a pastry: "Public service announcement for the ladies," scrawled on poorly edited icing. "Obesity isn't required to begin GLP-1 treatment."
In reality, however, it is required—at least per the U.S. Food and Drug Administration, which permits GLP-1 medications solely for individuals with diagnosed obesity, Type 2 diabetes, or those overweight with related health issues. Manufacturers of branded GLP-1 options such as Ozempic, Zepbound, and Wegovy have not extensively studied them on subjects with BMI below 27.
The paid promotions flooding my timeline, from telehealth providers including Willow, Noom, Fridays, EllieMD, and Midi Health, technically endorse a different item: pharmacist-compounded GLP-1 shots and pills. These lack FDA endorsement; they're tailored by chemists and typically contain reduced semaglutide amounts—the key component in Ozempic—mixed with additives. For instance, EllieMD provides a "longevity microdose" incorporating B12.
The FDA has issued a firm statement on this matter. "Compounded medications are appropriate only for patients whose requirements aren't addressed by approved FDA drugs," according to an FDA alert discouraging unapproved GLP-1 use for slimming.
Yet, the advertisements I've encountered primarily emphasize aesthetic transformations, not enhanced wellness. Certain ones highlight rapid shedding of a few pounds ahead of significant occasions, such as a marriage ceremony. Securing a prescription still involves consulting a physician, who evaluates your background and requirements. Willow's site openly declares the objective: "Effective medication for swift cosmetic reductions in size."
Willow, Noom, Fridays, and EllieMD declined to provide statements. Midi Health informed me they adopt a medical-centric, doctor-guided strategy for GLP-1 prescriptions. "Our physicians recommend these treatments due to evident clinical advantages and within a holistic plan for female wellness. GLP-1s are FDA-cleared for conditions beyond weight issues, like diabetes, sleep apnea, and sustained weight control...We understand BMI as a flawed metric meant for studies, not personalized treatment," Midi Health remarked.
To be equitable, the intense promotional efforts aren't confined to off-label substances. Back in 2023, following Ozempic's rise to fame, over 4,000 semaglutide marketing initiatives inundated online spaces. That year saw billboard promotions for "a weekly injection to slim down" dominating New York City's transit systems. Ro, the entity behind those efforts, now features video spots starring Serena Williams. It felt disheartening to have my television viewing disrupted by an intimate shot of the formidable athlete administering a substance that might lead to muscle depletion and exhaustion.


