📖Reference GuideUpdated 2026🔬Primary Sources First

Peptide Half-Life Chart

What the Published Data Actually Shows

A cautious reference for approved and studied peptides. Half-life varies by formulation, route, and study design, so use this as a starting point rather than a dosing rule.

Semaglutide
~1 week
FDA labeling reports an elimination half-life of approximately one week.
Tirzepatide
~5 days
FDA labeling reports an elimination half-life of about five days.
CJC-1295
Long-acting
Primary studies show prolonged GH and IGF-1 activity after subcutaneous administration.
Dashboard
Your complete health overview in one place
🔥
14-day streak
Logged 18 of 18 scheduled shots
Next Shot Reminder
ACTIVE MEDICATIONS
Peptide Half-Life ChartB12
PEPTIDE HALF-LIFE CHART
🔥 14
2
days away
Thursday · 7.5mg
Medication Supply
Peptide Half-Life Chart
6.2 / 10 mg · Vial
~42 days left · Mar 15
B12
4.4 / 5 ml · Vial
~88 days left · May 8
Retatrutide
1.2 / 5 mg · Vial
~6 days left · refill soon
Medication Levels
7 Days2 Weeks1 Month90 Days
CURRENT LEVEL
5.42mg
Mar 6
Today
ACTIVE MEDICATIONS
Peptide Half-Life ChartRetatrutide
0mg2.7mg5.4mg
18
Total Injections
💉 All time
122/78
Average BP
🩺 mmHg
8.4
Avg Mood
😊 /10
Health Chart
1mAll
218.6lb
↓ 8.4 lb · 3.7%
WeightInjectionsBPMood
2282222162102277.5mg7.5mg4mg10mg218
Feb 6Feb 14Feb 22Mar 2Today
Photos
12 photos · 2w streak
Week 1
Week 7
Today
Scheduled Reminders
Weight
Due today
Mood
Done
Blood Pressure
Tomorrow
Body Measurements
In 3 days
Dashboard
Your complete health overview in one place
🔥
14-day streak
Logged 18 of 18 scheduled shots
Next Shot Reminder
ACTIVE MEDICATIONS
Peptide Half-Life ChartB12
PEPTIDE HALF-LIFE CHART
🔥 14
2
days away
Thursday · 7.5mg
Medication Supply
Peptide Half-Life Chart
6.2 / 10 mg · Vial
~42 days left · Mar 15
B12
4.4 / 5 ml · Vial
~88 days left · May 8
Retatrutide
1.2 / 5 mg · Vial
~6 days left · refill soon
Medication Levels
7 Days2 Weeks1 Month90 Days
CURRENT LEVEL
5.42mg
Mar 6
Today
ACTIVE MEDICATIONS
Peptide Half-Life ChartRetatrutide
0mg2.7mg5.4mg
18
Total Injections
💉 All time
122/78
Average BP
🩺 mmHg
8.4
Avg Mood
😊 /10
Health Chart
1mAll
218.6lb
↓ 8.4 lb · 3.7%
WeightInjectionsBPMood
2282222162102277.5mg7.5mg4mg10mg218
Feb 6Feb 14Feb 22Mar 2Today
Photos
12 photos · 2w streak
Week 1
Week 7
Today
Scheduled Reminders
Weight
Due today
Mood
Done
Blood Pressure
Tomorrow
Body Measurements
In 3 days
01BACKGROUND

How To Read A Half-Life Chart

Half-life is a pharmacokinetic estimate, not a guarantee of effect duration. Route of administration, albumin binding, and formulation can change it materially.

For many research peptides, publicly available human PK data are limited or absent. If you cannot verify a label or primary study, treat the number as provisional rather than prescriptive.

02KEY NUMBERS

Examples With Published Data

📈
Semaglutide
0week
FDA labeling reports an elimination half-life of approximately one week.
💪
Tirzepatide
0days
FDA labeling reports an elimination half-life of about five days.
🏆
CJC-1295
0Long-acting
Primary studies show prolonged GH and IGF-1 activity after subcutaneous administration.
Research peptides
0Verify first
If a label or primary study is missing, do not assume a confident human half-life.
03MECHANICS

How To Use The Chart Safely

1
Start with the product label or primary study, not a social-media summary.
2
Separate the half-life of the molecule from the duration of the effect you are trying to measure.
3
Check the route and formulation before comparing two peptides side by side.
4
Use the chart as a reference for tracking, not as a substitute for prescribing guidance.
04WHY IT MATTERS

Why This Matters In Shotlee

When you log the dose, site, and timing of each injection in Shotlee, you can compare real-world response against the published timing window rather than relying on memory.

That makes it easier to spot whether a product is behaving like its label suggests or whether the formulation, route, or schedule needs to be reviewed with a clinician.

05FAQ

Guide FAQs

Not exactly. Half-life is a useful starting point, but the clinical effect can be longer or shorter depending on route, formulation, and downstream biology.

Only as a rough guide. If you cannot trace the number to a label or a primary study, treat it as provisional.

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📚References & sources

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