Shotlee LogoShotlee

Semaglutide Titration (Ozempic/Wegovy)

Semaglutide ScheduleWeekly Injection
Weeks 1-4
0.25mg
✓
✓
Initiation - let body adjust
Weeks 5-8
0.5mg
✓
✓
First increase
Weeks 9-12
1.0mg
✓ (max)
✓
Ozempic maintenance dose
Weeks 13-16
1.7mg
—
✓
Wegovy only
Week 17+
2.4mg
—
✓ (max)
Wegovy maintenance dose

Tirzepatide Titration (Mounjaro/Zepbound)

Tirzepatide ScheduleWeekly Injection
Weeks 1-4
2.5mg
Initiation dose
Weeks 5-8
5mg
First increase
Weeks 9-12
7.5mg
Optional step (may skip)
Weeks 13-16
10mg
Common maintenance dose
Weeks 17-20
12.5mg
Optional step
Week 21+
15mg
Maximum dose

Important Titration Tips

  • Don't rush: Each dose level should be maintained for at least 4 weeks to allow your body to adjust.
  • Side effects: If you experience severe nausea or vomiting, your doctor may extend your time at the current dose.
  • You can stay: Not everyone needs to reach the maximum dose. Many patients find success at lower doses.
  • Track everything: Use Shotlee to log your injections, side effects, and when you're scheduled to increase.

FAQ

When should I increase my Ozempic dose?

Following the standard schedule: increase from 0.25mg to 0.5mg after 4 weeks, then to 1.0mg after another 4 weeks. Your doctor may adjust this based on your response and side effects.

Can I skip doses in the Mounjaro titration?

Some providers skip the 7.5mg and 12.5mg steps, going directly from 5mg to 10mg, and 10mg to 15mg. This is common practice but should be discussed with your prescriber.

What if I miss a dose increase?

It's fine to stay at your current dose longer than 4 weeks. In fact, if you're tolerating it well and seeing good results, there's no need to rush the increase.

Never Miss a Titration Step

Shotlee automatically reminds you when it's time to increase your dose based on your start date.

🚀 Start Tracking Free