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Dose Escalation Calculator

Free Online Dose Escalation Calculator (2026)

Calculate when to increase your Ozempic or Mounjaro dose. Interactive titration schedule calculator with personalized timing.

Dashboard
Your complete health overview in one place
🔥
14-day streak
Logged 18 of 18 scheduled shots
Next Shot Reminder
ACTIVE MEDICATIONS
TirzepatideB12
TIRZEPATIDE
🔥 14
2
days away
Thursday · 7.5mg
Medication Supply
Tirzepatide
6.2 / 10 mg · Vial
~42 days left · Mar 15
B12
4.4 / 5 ml · Vial
~88 days left · May 8
Retatrutide
1.2 / 5 mg · Vial
~6 days left · refill soon
Medication Level Predictor
Estimated serum level & future decay
~5 days
Half-Life
7 Days2 Weeks1 Month90 Days
CURRENT LEVEL
5.42mg
Mar 6
● Today
ACTIVE MEDICATIONS
TirzepatideRetatrutide
TODAY5.42 mgFeb 14Feb 22Mar 14
0mg2.7mg5.42mg (Peak)
18
Total Injections
💉 All time
122/78
Average BP
🩺 mmHg
8.4
Avg Mood
😊 /10
Health Chart
1mAll
218.6lb
↓ 8.4 lb · 3.7%
WeightInjectionsBPMood
2282222162102277.5mg7.5mg4mg10mg218
Feb 6Feb 14Feb 22Mar 2Today
Photos
12 photos · 2w streak
Week 1
Week 7
Today
Scheduled Reminders
Weight
Due today
Mood
Done
Blood Pressure
Tomorrow
Body Measurements
In 3 days
Dashboard
Your complete health overview in one place
🔥
14-day streak
Logged 18 of 18 scheduled shots
Next Shot Reminder
ACTIVE MEDICATIONS
TirzepatideB12
TIRZEPATIDE
🔥 14
2
days away
Thursday · 7.5mg
Medication Supply
Tirzepatide
6.2 / 10 mg · Vial
~42 days left · Mar 15
B12
4.4 / 5 ml · Vial
~88 days left · May 8
Retatrutide
1.2 / 5 mg · Vial
~6 days left · refill soon
Medication Level Predictor
Estimated serum level & future decay
~5 days
Half-Life
7 Days2 Weeks1 Month90 Days
CURRENT LEVEL
5.42mg
Mar 6
● Today
ACTIVE MEDICATIONS
TirzepatideRetatrutide
TODAY5.42 mgFeb 14Feb 22Mar 14
0mg2.7mg5.42mg (Peak)
18
Total Injections
💉 All time
122/78
Average BP
🩺 mmHg
8.4
Avg Mood
😊 /10
Health Chart
1mAll
218.6lb
↓ 8.4 lb · 3.7%
WeightInjectionsBPMood
2282222162102277.5mg7.5mg4mg10mg218
Feb 6Feb 14Feb 22Mar 2Today
Photos
12 photos · 2w streak
Week 1
Week 7
Today
Scheduled Reminders
Weight
Due today
Mood
Done
Blood Pressure
Tomorrow
Body Measurements
In 3 days
01BACKGROUND

How to Use This Calculator

Use this page as a label-based dose-step helper for semaglutide and tirzepatide products. It helps you compare the current step with the next labeled step, but it does not replace your prescriber's instructions.

If your medication is compounded or prescribed off-label, follow the exact directions you were given rather than the brand-label schedule.

Save Your Results
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02MECHANICS

Step-by-Step Instructions

1
Enter your input values in the calculator above
2
Review the calculated results
3
Save your results to Shotlee for protocol tracking
4
Adjust values as needed for different scenarios
03DEEP DIVE

How to Use This Calculator Effectively

The useful comparison here is between your current dose and the label schedule for your specific product. That is why the calculator is a reference tool, not a dosing decision-maker.

Do not increase a dose just because the calendar says it is time. If you still have nausea, vomiting, or appetite suppression that is too strong, keep the current step and ask your clinician what to do next.

For brand-name products, compare the result with the FDA label. For compounded products, compare it with the written instructions from the pharmacy or prescriber.

04DEEP DIVE

How Fast Do Real Users Increase Their Dose?

Faster than official titration schedules suggest. Among 269 Shotlee users logging GLP-1 doses in milligrams, 77% — about 3 in 4 — moved up from their starting dose at some point in their logged history, and the median time to that first increase was just 21 days, roughly a week ahead of the 4-week step-up cadence on semaglutide and tirzepatide labels. Some of that reflects compounded or research protocols with faster schedules, and some reflects prescribers starting patients above the lowest rung. Whatever your schedule, log every dose change: appetite, side effects, and weight response often shift noticeably at each step, and that record is what lets you and your prescriber judge whether an increase actually helped. (Aggregated, anonymized Shotlee data as of July 2026.)

05FAQ

Frequently Asked Questions

Enter your values and get instant results. Save your calculations to Shotlee for protocol tracking.

Yes. All Shotlee calculators are free to use with no registration required.

The math is accurate for comparing a current dose to a label step-up schedule, but the right next step still depends on your exact medication, your response, and your clinician's advice.

Recalculate any time your prescription changes, you switch products, or your prescriber changes the titration pace.

Free · Always

Save Your Calculations in Shotlee

Track your complete protocol with free dose logging and calculation history.

📚References & sources

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