Larazotide (AT-1001) Tracker App

Larazotide (AT-1001) ist ein Peptid, das die Tight Junctions im Darm reguliert. Shotlee hilft Ihnen, dieses Protokoll lückenlos zu dokumentieren.

Tracken Sie Injektionsdaten, Dosen, Nebenwirkungen und Laborergebnisse. Saubere Daten ermöglichen eine bessere Optimierung Ihrer Darmgesundheit.

Kisspeptin refers to a family of neuropeptides derived from the KISS1 gene product via proteolytic cleavage. The principal forms are Kisspeptin-54 (54 amino acids, the full-length secreted form), Kisspeptin-14, Kisspeptin-13, and Kisspeptin-10 (the minimal bioactive C-terminal decapeptide). All forms bind the GPR54 receptor (also called KISS1R) and are equipotent at the receptor level.

Kisspeptin neurons in the arcuate nucleus and anteroventral periventricular nucleus of the hypothalamus project directly to GnRH neurons. When Kisspeptin binds GPR54 on these GnRH neurons, it triggers a robust GnRH pulse — the downstream signal that drives LH and FSH release from the pituitary, and ultimately testosterone (in testes) and estradiol (in ovaries). Disruptions in Kisspeptin signaling cause hypogonadotropic hypogonadism — low testosterone/estrogen with normal or low LH/FSH.

The discovery of Kisspeptin's role in reproductive biology came from studying humans with KISS1 or KISS1R loss-of-function mutations — who all had complete hypogonadotropic hypogonadism (no puberty, no sex hormone production). This confirmed Kisspeptin as the master gate controlling the entire reproductive endocrine system — now the subject of intense clinical research for fertility treatment, sex hormone optimization, and endocrine dysfunction.

Pulsatile dosing is critical — continuous use will suppress rather than stimulate. Use Shotlee to track dose timing and LH/testosterone lab results. All human use is experimental research off-label application.