GLP-1 / GIP🔬Investigational🏢Roche

CT-388 Tracker

Roche’s weekly dual agonist — and your protocol today

CT-388 is a once-weekly injectable GLP-1/GIP dual receptor agonist developed by Roche (acquired through Carmot Therapeutics) — the same dual-receptor class as tirzepatide. It is investigational and not FDA approved. Shotlee is the free app to track your current protocol while it advances.

25,000+GLP-1 Users Tracking
4.8★App Rating
FreeAlways Free
GLP-1 Users Tracking
25,000+
App Rating
4.8★
Always Free
Free
Dashboard
Your complete health overview in one place
🔥
14-day streak
Logged 18 of 18 scheduled shots
Next Shot Reminder
ACTIVE MEDICATIONS
TirzepatideB12
TIRZEPATIDE
🔥 14
2
days away
Thursday · 7.5mg
Medication Supply
Tirzepatide
6.2 / 10 mg · Vial
~42 days left · Mar 15
B12
4.4 / 5 ml · Vial
~88 days left · May 8
Retatrutide
1.2 / 5 mg · Vial
~6 days left · refill soon
Medication Levels
7 Days2 Weeks1 Month90 Days
CURRENT LEVEL
5.42mg
Mar 6
Today
ACTIVE MEDICATIONS
TirzepatideRetatrutide
0mg2.7mg5.4mg
18
Total Injections
💉 All time
122/78
Average BP
🩺 mmHg
8.4
Avg Mood
😊 /10
Health Chart
1mAll
218.6lb
↓ 8.4 lb · 3.7%
WeightInjectionsBPMood
2282222162102277.5mg7.5mg4mg10mg218
Feb 6Feb 14Feb 22Mar 2Today
Photos
12 photos · 2w streak
Week 1
Week 7
Today
Scheduled Reminders
Weight
Due today
Mood
Done
Blood Pressure
Tomorrow
Body Measurements
In 3 days
Dashboard
Your complete health overview in one place
🔥
14-day streak
Logged 18 of 18 scheduled shots
Next Shot Reminder
ACTIVE MEDICATIONS
TirzepatideB12
TIRZEPATIDE
🔥 14
2
days away
Thursday · 7.5mg
Medication Supply
Tirzepatide
6.2 / 10 mg · Vial
~42 days left · Mar 15
B12
4.4 / 5 ml · Vial
~88 days left · May 8
Retatrutide
1.2 / 5 mg · Vial
~6 days left · refill soon
Medication Levels
7 Days2 Weeks1 Month90 Days
CURRENT LEVEL
5.42mg
Mar 6
Today
ACTIVE MEDICATIONS
TirzepatideRetatrutide
0mg2.7mg5.4mg
18
Total Injections
💉 All time
122/78
Average BP
🩺 mmHg
8.4
Avg Mood
😊 /10
Health Chart
1mAll
218.6lb
↓ 8.4 lb · 3.7%
WeightInjectionsBPMood
2282222162102277.5mg7.5mg4mg10mg218
Feb 6Feb 14Feb 22Mar 2Today
Photos
12 photos · 2w streak
Week 1
Week 7
Today
Scheduled Reminders
Weight
Due today
Mood
Done
Blood Pressure
Tomorrow
Body Measurements
In 3 days
01BACKGROUND

What is CT-388?

CT-388 is a once-weekly injectable GLP-1/GIP dual receptor agonist that Roche obtained through its acquisition of Carmot Therapeutics. It targets the same two receptors as tirzepatide (Mounjaro/Zepbound), combining appetite suppression with the GIP-driven metabolic effect.

CT-388 reported strong early-phase weight loss and is part of Roche’s broader obesity portfolio, which also includes the oral CT-996 and the amylin analog petrelintide. It is one of the most-watched injectable dual agonists behind the approved tirzepatide and investigational retatrutide.

⚠️
Investigational — not yet available
CT-388 is in clinical development and is not FDA approved or prescribable. Use Shotlee to track your current GLP-1 protocol and build baseline data while you follow its progress.
02KEY NUMBERS

CT-388 Key Facts

📈
Class
0+ GIP
Once-weekly injectable dual agonist
💪
Developer
Roche
Acquired via Carmot Therapeutics
🏆
Status
Investigational
In clinical trials; not FDA approved
03WHAT TO TRACK

What to Track in Shotlee

Build clean baseline data now so you can compare if next-gen dual agonists reach the market.

01
💉
Dose Logs
Record every injection date, dose, and site with reminders.
02
⚖️
Weekly Weight
Track weight consistently to build your personal response curve.
03
🤢
Side Effects
Log GI symptoms and severity to share with your prescriber.
04
🩸
Lab Results
Save HbA1c, glucose, and lipids from clinic visits in one place.
05
📐
Measurements
Waist, hip, and neck measurements reveal changes the scale misses.
06
😴
Appetite & Energy
Daily ratings show how well your protocol controls cravings.
04TIMELINE

Development Outlook

Early phase
CT-388 reported strong early GLP-1/GIP weight-loss data after Roche’s Carmot acquisition.
Now
Advancing in trials; dose, durability, and safety are being characterized.
Next
If later trials confirm efficacy and safety, regulatory submission and review could follow.
05FAQ

Protocol FAQs

CT-388 is Roche’s once-weekly injectable GLP-1/GIP dual receptor agonist (from the Carmot Therapeutics acquisition), in clinical development for obesity. It targets the same receptors as tirzepatide and is investigational, not FDA approved.

Both are GLP-1/GIP dual agonists, but CT-388 is a different molecule from Roche and is still investigational, while tirzepatide (Mounjaro/Zepbound) is FDA approved and available. No head-to-head data exists.

No. Both are Roche obesity candidates, but CT-388 is an injectable GLP-1/GIP dual agonist, while CT-996 is an oral small-molecule GLP-1 agonist.

It is investigational and only available in trials. Timing depends on later-stage results and regulatory review. Follow Shotlee’s tracker pages for updates.

Yes. Shotlee logs doses, weight, side effects, and labs for your current medication for free, so you have a clean baseline if next-gen dual agonists like CT-388 launch.

Free · Always

Track Your Protocol in Shotlee

Free dose logs, weight trends, and side effect tracking — ready for the next-gen dual agonists.

📚References & sources

Start tracking