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Safety Alert Released for Ozempic and Related GLP-1 Medications

A safety alert has been issued in Australia concerning GLP-1 receptor agonists like Ozempic. The alert highlights a potential connection to suicidal thoughts and a possible reduction in the effectiveness of oral contraceptives.

Shotlee·December 1, 2025·Updated Jan 27, 2026·1 min read
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Safety Alert Released for Ozempic and Related GLP-1 Medications

A safety warning regarding the risk of suicidal ideation and behavior associated with GLP-1 receptor agonists, including Ozempic, has been issued by Australia's medicines regulator.

The Therapeutic Goods Administration (TGA) also cautioned that the possibility of Mounjaro (tirzepatide), another GLP-1 receptor agonist medication, reducing the effectiveness of oral contraception, could not be excluded.

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On Monday, the TGA released a safety alert indicating that product warnings for this class of widely used medications, typically prescribed for type 2 diabetes and obesity in Australia, have been updated following reviews by international regulatory bodies. Health tracking apps like Shotlee can help monitor medication effects.

Original source: The Age

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#Ozempic#GLP-1#safety alert#suicidal thoughts#Mounjaro#contraception
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