A hot drink costing just 4p might mimic the effects of popular GLP-1 inhibitors for weight loss, according to recent research. This scientific review highlights natural dietary compounds that replicate GLP-1 actions, offering potential accessible options.
What Are GLP-1 Inhibitors?
GLP-1 (glucagon-like peptide-1) is a gut hormone that regulates blood sugar and appetite. GLP-1 inhibitors, now commonly called agonists, have gained popularity for managing diabetes and promoting weight loss through injections.
Available via the NHS for eligible patients, these medications like semaglutide (Ozempic, Wegovy) and tirzepatide (Mounjaro) effectively control blood sugar and reduce appetite. Yet, high costs and side effects like vomiting, diarrhea, and cramps prompt interest in natural alternatives.
2025 Research on Natural GLP-1 Mimics
Researchers from Heliopolis University in Cairo published a review in Toxicology Reports in 2025. They examined how dietary compounds influence GLP-1 secretion, aiming to improve treatment accessibility and personalization.
The study notes: "It's about increasing treatment options and personalising it to each patient's preferences and needs." This approach could reduce reliance on expensive injections.
Foods and Drinks That May Boost GLP-1
- Green tea
- Ginger
- Cinnamon
- Wheat
- Berberine (found in certain plants)
These compounds were identified as potentially enhancing GLP-1 effects, as reported by Medical News Today.
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Expert Caution on Natural Alternatives
Bariatric surgeon Mir Ali, MD, medical director at Memorial Care Surgical Weight Loss Centre, emphasizes limitations. He states: "Natural ingredients may help boost metabolism. However, it is a mild effect. These [compounds] should not be considered an alternative to the GLP-1 medications."
Ali explains they work differently—caffeine stimulates the central nervous system, green tea extract promotes fat burning, and berberine activates enzymes.
Supporting Evidence from Green Tea Studies
Prior research links green tea to weight loss benefits. A study in the Journal of Functional Foods found catechin-enriched green tea significantly reduced visceral fat, body weight, and body fat in adults with high abdominal fat.
Authors reported: "Average visceral fat area, body weight, and body fat were reduced significantly... The decrease at week 12 in the visceral fat area in the catechin group was greater than that in the control group."
They added: "In recent years, there have been many studies on the beneficial effects of green tea in treating obesity and improving glucose and lipid metabolism."
At reporting, a pack of 20 green tea bags cost 80p, or 4p per cup.